Thermo-Responsive Hydrogel Layers Imprinted with RGDS Peptide: A System for Harvesting Cell Sheets

Thermo-Responsive Hydrogel Layers Imprinted with RGDS Peptide: A System for Harvesting Cell Sheets
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印有 RGDS 肽的热响应水凝胶层:用于收获细胞片的系统

DOI:
10.1002/anie.201300733
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发表时间:
2013-01-01
影响因子:
16.6
通讯作者:
Li, Bin
Li, Bin
中科院分区:
化学1区
文献类型:
--
作者:
Pan, Guoqing;Guo, Qianping;Li, Bin

文献摘要

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本文提供了关于将细胞粘附肽Arg-Gly-Asp-Ser(RGDS)引入到温敏细胞培养基质上的信息,所述温敏细胞培养基质用作收获细胞片层的新系统。它提到,分子印迹聚合物(MIPs)的热响应亲和力的引入在细胞培养期间促进细胞的粘附。它还指出,它有助于细胞分离。
The article offers information on the introduction of the cell adhesive peptide Arg-Gly-Asp-Ser (RGDS) onto a thermo-responsive cell culture substrate which was used as a novel system for harvesting cell sheets. It mentions that the introduction of thermo-responsive affinity of the molecularly imprinted polymers (MIPs) promotes adhesion of cells during cell culture. It also states that it facilitate cell detachment.