Preoperative systemic inflammatory response index predicts long-term outcomes in type B aortic dissection after endovascular repair.
Preoperative systemic inflammatory response index predicts long-term outcomes in type B aortic dissection after endovascular repair.
复制标题
术前全身炎症反应指数可预测B型主动脉夹层腔内修复术后的长期结局
DOI：
10.3389/fimmu.2022.992463
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发表时间：
2022
影响因子：
7.3
通讯作者：
Wang, Lixin
中科院分区：
文献类型：
--
作者：
Zhao, Yufei;Hong, Xiang;Xie, Xinsheng;Guo, Daqiao;Chen, Bin;Fu, Weiguo;Wang, Lixin
关键词：
Inflammation is a hallmark of the initial development and progression of aortic dissection. This study aimed to investigate the value of preoperative inflammatory biomarkers in predicting aorta-related adverse events (AAEs) after thoracic endovascular aortic repair (TEVAR) for type B aortic dissection. We included all patients who underwent TEVAR for type B aortic dissection between November 2016 and November 2020 in this single-center, retrospective cohort study. Patients were divided into two groups: the AAEs group (n = 75) and the non-AAEs group (n = 126). Preoperative inflammatory biomarkers were recorded, including neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), platelet-to-lymphocyte ratio (PLR), systemic immune inflammation index (SII), and systemic inflammatory response index (SIRI). Patients were followed-up for the development of AAEs. Prediction accuracy of inflammatory biomarkers for AAEs were evaluated using the area under the receiver operating characteristic curves. This study included 201 patients, of whom 80.0% were men, with a mean age of 59.1 ± 12.5 years. A total of 75 patients developed AAEs after TEVAR. The AUCs of NLR, MLR, PLR, SII, and SIRI for AAEs were.746,.782,.534,.625 and.807, respectively. Age and SIRI were independent risk factors for the AAEs after TEVAR (HR 3.264, p <.001; HR 4.281, p <.001, respectively). Survival analysis revealed significantly lower AAE-free status in patients with preoperative SIRI > = 4 (p <.001). Increased preoperative SIRI and age are independent risk factors for AAEs after TEVAR in type B aortic dissection. This study investigated the value of preoperative inflammatory biomarkers NLR, MLR, PLR, SII, and SIRI in predicting aorta-related adverse events (AAEs) after thoracic endovascular aortic repair (TEVAR) for type B aortic dissection. The increased SIRI and age were independently associated with postoperative AAEs after TEVAR. Preoperative SIRI serves as an effective prognostic risk factor in patients with type B aortic dissection.
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影响因子：
4.6
作者：
Li S;Yang J;Dong J;Guo R;Chang S;Zhu H;Li Z;Zhou J;Jing Z
通讯作者：
Jing Z
DOI：
10.1038/s41569-021-00589-2
发表时间：
2022-01
期刊：
Nature reviews. Cardiology
影响因子：
--
作者：
Fernandez DM;Giannarelli C
通讯作者：
Giannarelli C
影响因子：
--
作者：
Jiang, Yun-Fei;Guo, Ling-Ling;Jing, Zai-Ping
通讯作者：
Jing, Zai-Ping
影响因子：
39.3
作者：
Erbel, Raimund;Aboyans, Victor;Vrints, Christiaan J. M.
通讯作者：
Vrints, Christiaan J. M.
影响因子：
39.3
作者：
Adamstein, Nicholas H.;MacFadyen, Jean G.;Ridker, Paul M.
通讯作者：
Ridker, Paul M.