Central nervous system imaging findings of hemophagocytic syndrome
Central nervous system imaging findings of hemophagocytic syndrome
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DOI：
10.1016/j.clinimag.2015.07.013
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发表时间：
2015-11-01
期刊：
影响因子：
2.1
通讯作者：
Kaufmann, Timothy J.
中科院分区：
文献类型：
--
作者：
Anderson, Tara L.;Carr, Carrie M.;Kaufmann, Timothy J.
我们介绍了一例罕见的成人噬血细胞淋巴组织细胞增生症（HLH）累及颅内的病例。HLH的MRI特征可能与其他肿瘤性、感染性或炎性疾病相似。主要影像学表现与中枢神经系统炎症相关，包括弥漫性软脑膜强化、白色物质改变伴不同程度强化、出血和弥散受限。识别与临床表现、实验室检查值和活检结果相关的影像学特征对于做出正确诊断至关重要。(C)2015 Elsevier Inc. All rights reserved.
We present a rare case of intracranial involvement in hemophagocytic lymphohistiocytosis (HLH) in an adult patient. MRI features in HLH may mimic those of other neoplastic, infectious, or inflammatory disorders. Key imaging findings correlate to central nervous system inflammation and include diffuse leptomeningeal enhancement, white matter changes with variable enhancement, hemorrhage, and restricted diffusion. Recognition of the imaging characteristic in correlation with clinical presentation, laboratory values, and biopsy findings is essential for making a correct diagnosis. (C) 2015 Elsevier Inc. All rights reserved.