Low-density lipoprotein triglycerides associated with low-grade systemic inflammation, adhesion molecules, and angiographic coronary artery disease -: The Ludwigshafen Risk and Cardiovascular Health study
Low-density lipoprotein triglycerides associated with low-grade systemic inflammation, adhesion molecules, and angiographic coronary artery disease -: The Ludwigshafen Risk and Cardiovascular Health study
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DOI：
10.1161/01.cir.0000146898.06923.80
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发表时间：
2004-11-09
期刊：
影响因子：
37.8
通讯作者：
Winkelmann, BR
中科院分区：
文献类型：
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作者：
März, W;Scharnagl, H;Winkelmann, BR
背景-全身炎症标志物和低密度脂蛋白胆固醇（LDL-C）被认为是冠状动脉疾病（CAD）的独立危险因素。我们研究了LDL代谢的改变不反映LDL-C是否与低度炎症，血管损伤，和CAD.Methods和结果，我们研究了739例稳定的血管造影CAD和570匹配的对照组，其中CAD已被排除血管造影。低密度脂蛋白甘油三酯（LDL-TG）与低密度脂蛋白胆固醇（LDL-TG）的相关性（比值比[OR]，1.30; 95%CI，1.19至1.43; P
Background-Markers of systemic inflammation and LDL cholesterol (LDL-C) have been considered independent risk factors of coronary artery disease (CAD). We examined whether alterations of LDL metabolism not reflected by LDL-C were associated with low-grade inflammation, vascular injury, and CAD.Methods and Results-We studied 739 subjects with stable angiographic CAD and 570 matched control subjects in which CAD had been ruled out by angiography. The association of LDL triglycerides (LDL-TGs) (odds ratio [OR], 1.30; 95% CI, 1.19 to 1.43; P