Aeromonas spp.: ubiquitous or specialized bugs?
Aeromonas spp.: ubiquitous or specialized bugs?
复制标题
DOI：
10.1111/1462-2920.12215
复制
发表时间：
2014-04-01
影响因子：
5.1
通讯作者：
Cardazzo, Barbara
中科院分区：
文献类型：
--
作者：
Martino, Maria Elena;Fasolato, Luca;Cardazzo, Barbara
气单胞菌属包括已知在环境中起几种作用的普遍存在的细菌。这些细菌最初被描述为鱼类病原体，但它们在其他宿主（如动物和人类）中的存在也有记录。今天，这些细菌被描述为新兴的病原体，但它们在人类致病性中的有效作用仍然存在争议。此外，它们的分类也有很大的争议，因为物种的区分往往很难实现。为了研究气单胞菌的种间关系，并探讨其与环境的关系，一个多位点序列分型方案先前开发的气单胞菌。对258个菌株进行了遗传分析。采样是一个基本步骤，包括气单胞菌的几个主要来源：鱼类、食品和人类病例。其目的是描述分离株的特征，并根据以下内容找到它们之间的潜在关联：物种、毒力因子的共享、来源和对特定栖息地的适应。对菌株进行了表征，并证明气单胞菌属中的核苷酸变异性异常高。在取样的来源中，发现了不同的物种分布，突出了对特定生境的适应过程的发生。
The genus Aeromonas comprises ubiquitous bacteria that are known to play several roles in the environment. These bacteria were first described as fish pathogens, but their presence was documented in other reservoirs, such as animals and humans. Today, these bacteria are described as emerging pathogens, but their effective role in human pathogenicity is still controversial. In addition, their taxonomy is heavily debated, as species distinction is often difficult to achieve. To study the interspecies relationships and to investigate their connection with the environment, a multilocus sequence typing scheme previously developed for Aeromonas spp. was applied to 258 strains, and the genetic data were analysed by population software. Sampling was a fundamental step, including several of the main sources of Aeromonas: fish, food products and human cases of disease. The objective was to characterize the isolates and to find potential associations among them according to the following: species, sharing of virulence factors, source and adaptation to a specific habitat. The strains were characterized and demonstrated exceptionally high nucleotide variability in the Aeromonas genus. Among the sampled sources, different species distributions were found, highlighting the occurrence of adaptation processes towards specific habitats.