Carbachol, an acetylcholine receptor agonist, enhances production in rat aorta of 2-arachidonoyl glycerol, a hypotensive endocannabinoid
Carbachol, an acetylcholine receptor agonist, enhances production in rat aorta of 2-arachidonoyl glycerol, a hypotensive endocannabinoid
复制标题
DOI：
10.1016/s0014-2999(98)00777-8
复制
发表时间：
1998-11-27
影响因子：
5
通讯作者：
Horowitz, M
中科院分区：
文献类型：
--
作者：
Mechoulam, R;Fride, E;Horowitz, M
2-花生四烯酸甘油，内源性大麻素的生产，是增强正常的，但不是在内皮剥脱大鼠主动脉上的刺激与卡巴胆碱，乙酰胆碱受体激动剂。2-花生四烯酰甘油有效降低大鼠血压，可能是一种内皮源性膨胀因子。(C)1998 Elsevier Science B. V.保留所有权利。
The production of 2-arachidonoyl glycerol, an endogenous cannabinoid, is enhanced in normal, but not in endothelium-denuded rat aorta on stimulation with carbachol, an acetylcholine receptor agonist. 2-Arachidonoyl glycerol potently reduces blood pressure in rats and may represent an endothelium-derived hypotensive factor. (C) 1998 Elsevier Science B.V. All rights reserved.