Listeria monocytogenes σB contributes to invasion of human intestinal epithelial cells
Listeria monocytogenes σB contributes to invasion of human intestinal epithelial cells
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DOI：
10.1128/iai.72.12.7374-7378.2004
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发表时间：
2004-12-01
影响因子：
3.1
通讯作者：
Marquis, H
中科院分区：
文献类型：
--
作者：
Kim, H;Boor, KJ;Marquis, H
研究了（B）在单核细胞增生李斯特菌感染人肠上皮细胞中的作用。与GB缺失相关的侵袭缺陷与Deltain14菌株的侵袭缺陷不同，与σ（B）依赖性P2（prfA）启动子无关。同时，在DeltasigB菌株中inlA转录物和InlA蛋白的量显著降低。
The role of (B) in Listeria monocytogenes infection of human intestinal epitheliall cells was investigated. Invasion defects associated with loss of GB paralleled those of a Deltainl4 strain independently of the sigma(B)-dependent P2(prfA) promoter. Concomitantly, amounts of inlA transcript and InlA protein were significantly decreased in the DeltasigB strain.