An Efficient PIFA-Mediated Synthesis of a Directly Linked Zinc Chlorin Dimer via Regioselective Oxidative Coupling
An Efficient PIFA-Mediated Synthesis of a Directly Linked Zinc Chlorin Dimer via Regioselective Oxidative Coupling
复制标题
通过区域选择性氧化偶联，PIFA 介导的直接连接的二氯锌二聚体的高效合成
DOI：
10.1021/ol300969g
复制
发表时间：
2012-06-01
期刊：
影响因子：
5.2
通讯作者：
Zheng, Jian-Yu
中科院分区：
文献类型：
--
作者：
Ouyang, Qin;Yan, Kai-Qi;Zheng, Jian-Yu
通过氯化锌单体与苯基碘二（三氟乙酸酯）（PIFA）的简单有效的氧化偶联，首次合成了直接连接的氯化锌二聚体。该反应在氢化吡咯环附近的20位具有较高的区域选择性，产率为74%。
The synthesis of a directly linked zinc chlorin dimer was first achieved by a facile and efficient oxidative coupling of zinc chlorin monomers with phenyliodine bis(trifluoroacetate) (PIFA). The reaction shows high regioselectivity at the 20-position near the hydrogenated pyrrole ring producing selective dichlorin in 74% yield.