Effect of different solvents on poly(caprolactone) (PCL) electrospun nonwoven membranes
Effect of different solvents on poly(caprolactone) (PCL) electrospun nonwoven membranes
复制标题
不同溶剂对聚己内酯（PCL）电纺非织造膜的影响
DOI：
10.1007/s10973-011-1640-4
复制
发表时间：
2012-03-01
影响因子：
4.4
通讯作者：
Wu, Dequn
中科院分区：
文献类型：
--
作者：
Qin, Xiaohong;Wu, Dequn
聚己内酯（PCL）是一种生物可降解、生物相容性好的高分子材料，因其对环境友好而受到广泛关注，并在生物医学领域得到广泛应用。静电纺丝是一种直接从聚合物溶液中制备纳米纤维的方法，其纳米纤维的尺寸在100 nm左右的亚微米范围内。然而，还没有建立明确的标准来判断对聚合物具有高溶解度的溶剂是否会产生有利于静电纺丝的溶液。针对上述原因，本文探讨了溶剂对PCL电纺非织造膜纤维形态、FT-IR和1H NMR谱、粘度和剪切强度、差示扫描量热（DSC）的影响。当以NMP和AC为溶剂进行静电纺丝时，它们都是由具有相似纤维表面形貌的光滑纳米纤维组成。同时，当使用DCM和CF作为溶剂时，由于高蒸发，纤维中存在大量的孔。由于CA的粘度最低，所以选择CA作为溶剂时，可纺性较好。
Poly(caprolactone) (PCL) is one of biodegradable and biocompatible polymers, which have received significant attention because they are environmentally friendly and are extensively used in biomedical applications. Electrospinning was a straightforward method to produce nanofibers from polymer solutions in a wide submicron range around 100 nm. However, no clear standard had been established for judging whether a solvent of high solubility for a polymer would produce a solution good for electrospinning. Considering the above-mentioned cause, we explored the effect of solvent on fibrous morphology, FT–IR spectra and 1H NMR spectra, viscosity and shearing strength, differential scanning calorimetry (DSC) of PCL electrospun nonwoven membranes in this article. When NMP and AC were used as the solvent for PCL electrospinning, all of them were composed of smooth and nanosized fibers with similar fiber surface morphologies. Meanwhile, when DCM and CF were used as solvent, there were lots of holes in fibers due to high evaporation. The electrospinnability was good when CA was chosen as solvent due to its lowest viscosity.