Increasing weight-bearing physical activity and calcium intake for bone mass growth in children and adolescents: A review of intervention trials
Increasing weight-bearing physical activity and calcium intake for bone mass growth in children and adolescents: A review of intervention trials
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DOI：
10.1006/pmed.2000.0758
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发表时间：
2000-12-01
影响因子：
5.1
通讯作者：
Story, M
中科院分区：
文献类型：
--
作者：
French, SA;Fulkerson, JA;Story, M
目标。本综述的目的是评估目前科学水平的干预措施，以增加骨量增加儿童和青少年使用负重体育活动或补钙。研究是通过计算机化和人工搜索经验文献来定位的。纳入标准为：(a)针对负重体力活动或钙摄入的干预研究；(b)纳入对照组；(c)受试者年龄在18岁以下；(d)结果测量骨矿物质密度或骨矿物质含量。结果：负重体育活动和补钙干预研究都一致显示对儿童和青少年骨量增加有积极作用。在负重运动和补钙方面最一致的发现是腰椎和全身骨骼部位。只有负重体力活动干预对股骨颈部位有显著影响。在一些研究中，低功率可能导致缺乏统计上显著的发现，也妨碍了对青春期状态与骨量增加干预之间潜在相互作用的适当评估。增加负重体力活动或钙摄入量对儿童和青少年的骨量增加有积极影响。需要进一步的研究来评价：(a)这些影响的长期持久性；(b)特定剂量-反应关联；(c)负重体力活动与钙摄入量之间的相互作用；(d)青春期发育与负重体力活动或钙摄入量对骨量结果的相互作用，(C) 2000年美国健康基金会和学术出版社。
Objective. The purpose of this review is to evaluate the current state-of-the-science for interventions to increase bone mass gains in children and adolescents using weight-bearing physical activity or calcium supplementation.Methods. Studies were located using computerized and manual searches of the empirical literature. Inclusion criteria were: (a) intervention study targeting weight-bearing physical activity or calcium intake; (b) inclusion of a control group; (c) subject age range under 18 years; and (d) outcome measured bone mineral density or bone mineral content.Results, Weight-bearing physical activity and calcium supplement intervention studies both consistently show positive effects on bone mass gains in children and adolescents. The most consistent findings for both weight-bearing physical activity and calcium were for lumbar spine and total body bone sites. Only weight-bearing physical activity interventions had significant effects on the femoral neck sites. Low power may have contributed to the lack of statistically significant findings in several studies and also prevented proper evaluation of potential interactions between pubertal status and interventions on bone mass gains.Conclusions. Increases in weight-bearing physical activity or calcium intake have positive effects on bone mass gains in children and adolescents. Further research is needed to evaluate: (a) the long-term durability of these effects; (b) specific dose-response associations; (c) interactions between weight-bearing physical activity and calcium intake; and (d) interactions between pubertal development and weight-bearing physical activity or calcium intake on bone mass outcomes, (C) 2000 American Health Foundation and Academic Press.