On the intrinsic sterility of 3D printing

On the intrinsic sterility of 3D printing
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DOI:
10.7717/peerj.2661
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发表时间:
2016-12-01
期刊:
影响因子:
2.7
通讯作者:
Pudlo, Nicholas
Pudlo, Nicholas
中科院分区:
生物学3区
文献类型:
--
作者:
Neches, Russell Y.;Flynn, Kaitlin J.;Pudlo, Nicholas

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使用挤出热塑性塑料构建物体的3D打印机正在迅速成为实验室中的常用工具。我们证明,通过适当的处理,这些器械能够从非无菌热塑性原料生产无菌组件,而无需在制造后进行任何处理。制造过程本身导致材料灭菌。由此产生的3D打印组件适用于各种应用,包括细菌和细胞培养实验。
3D printers that build objects using extruded thermoplastic are quickly becoming commonplace tools in laboratories. We demonstrate that with appropriate handling, these devices are capable of producing sterile components from a non-sterile feedstock of thermoplastic without any treatment after fabrication. The fabrication process itself results in sterilization of the material. The resulting 3D printed components are suitable for a wide variety of applications, including experiments with bacteria and cell culture.