New endemic foci of schistosomiasis infections in the Philippines
New endemic foci of schistosomiasis infections in the Philippines
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DOI：
10.1016/j.actatropica.2013.03.015
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发表时间：
2015-01-01
期刊：
影响因子：
2.7
通讯作者：
Velayudhan, Raman
中科院分区：
文献类型：
--
作者：
Leonardo, Lydia;Rivera, Pilarita;Velayudhan, Raman
菲律宾东南部沿着有28个省受到血吸虫病的影响，那里全年降雨不断。2002年和2005年，分别在最北部（贡扎加，卡加延）和中部（卡拉特拉瓦，西内格罗斯）报告了两个新的地方性疫源地。通过对7个新发流行村可能的钉螺栖息地进行钉螺调查，确定了湖北钉螺。通过粪便检查的动物调查证实了贡扎加动物中存在血吸虫病感染，但在卡拉特拉瓦没有。与卡拉特拉瓦相比，使用所有四种诊断方法，贡扎加表现出明显更高的血吸虫病患病率。钉螺栖息地靠近人类居住地，包括较高的钉螺密度和钉螺感染率，可能是导致高流行率的原因。蜗牛的网站更广泛的贡扎加，而在卡拉特拉瓦仅限于一般人口，但农民经常光顾的地区。显示贡扎加和卡拉特拉瓦的蜗牛空间分布的GIS地图显示了蜗牛站点之间的海拔差异。人们从流行省份迁移到贡扎加和卡拉特拉瓦带来了病例，在存在蜗牛中间宿主的情况下，疾病的出现只是时间问题。(C)2013爱思唯尔有限公司版权所有。
Schistosomiasis affects 28 provinces in the Philippines found along the southeastern part where there is continuous rainfall throughout the year. In 2002 and 2005 respectively, two new endemic foci were reported in the northernmost (Gonzaga, Cagayan) and central (Calatrava, Negros Occidental) parts of the country.This study conducted in March 2008 March 2009 confirmed the presence of the disease by determining its prevalence using four diagnostic tests - Kato-Katz, circumoval precipitin test (COPT), ELISA and ultrasonography. Oncomelania hupensis quadrasi was identified through snail surveys conducted in possible snail habitats in the seven new endemic villages. Animal surveys through stool examination confirmed the presence of schistosomiasis infection in animals in Gonzaga but not in Calatrava.Compared to Calatrava, Gonzaga demonstrated markedly higher prevalence of schistosomiasis using all four diagnostic methods. Proximity of snail habitats to human habitation including higher snail density and snail infection rate could be responsible for the high prevalence. Snail sites were more widespread in Gonzaga whereas those in Calatrava were confined only in areas not frequented by the general population except by farmers. GIS maps showing spatial distribution of snails in Gonzaga and Calatrava indicated differences in elevation among the snail sites.It is hypothesized that the snail intermediate host has been in these sites for sometime but discovered only lately. Migration of people from endemic provinces into Gonzaga and Calatrava brought in cases and in the presence of snail intermediate hosts, emergence of disease was just a matter of time. (C) 2013 Elsevier B.V. All rights reserved.