Renal association clinical practice guideline in post-operative care in the kidney transplant recipient

Renal association clinical practice guideline in post-operative care in the kidney transplant recipient
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DOI:
10.1186/s12882-017-0553-2
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发表时间:
2017-06-02
期刊:
影响因子:
2.3
通讯作者:
Palmer, Nicholas
Palmer, Nicholas
中科院分区:
医学4区
文献类型:
--
作者:
Baker, Richard J.;Mark, Patrick B.;Palmer, Nicholas

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这些指南涵盖了从肾移植后到移植不再起作用或患者死亡期间的患者护理。在早期阶段,预防急性排斥反应和感染是优先考虑的。大约3-6个月后,优先考虑的是保护移植功能和避免免疫抑制药物(用于抑制免疫系统以防止排斥反应的药物)的长期并发症。讨论的主题包括门诊随访的组织,免疫抑制药物,急性和慢性排斥反应的治疗,以及并发症的预防。讨论的潜在并发症包括心脏病、感染、癌症、骨骼疾病和血液疾病。还有一个关于避孕和生殖问题的章节,在导言之后,紧接着是所有建议的说明。这些建议是用我们认为应该被许多患者,亲属,护理人员和其他感兴趣的人理解的语言编写的。因此,我们没有在本非正式摘要中重新措辞或重述它们。根据作者推荐的强度,它们被分为1级或2级,而AD则取决于推荐所基于的证据的质量。
These guidelines cover the care of patients from the period following kidney transplantation until the transplant is no longer working or the patient dies. During the early phase prevention of acute rejection and infection are the priority. After around 3-6 months, the priorities change to preservation of transplant function and avoiding the long-term complications of immunosuppressive medication (the medication used to suppress the immune system to prevent rejection). The topics discussed include organization of outpatient follow up, immunosuppressive medication, treatment of acute and chronic rejection, and prevention of complications. The potential complications discussed include heart disease, infection, cancer, bone disease and blood disorders. There is also a section on contraception and reproductive issues.Immediately after the introduction there is a statement of all the recommendations. These recommendations are written in a language that we think should be understandable by many patients, relatives, carers and other interested people. Consequently we have not reworded or restated them in this lay summary. They are graded 1 or 2 depending on the strength of the recommendation by the authors, and AD depending on the quality of the evidence that the recommendation is based on.