Potential biological functions emerging from the different estrogen receptors

Potential biological functions emerging from the different estrogen receptors
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DOI:
10.1196/annals.1365.033
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发表时间:
2006-01-01
期刊:
WOMEN'S HEALTH AND DISEASE: GYNECOLOGIC, ENDOCRINE, AND REPRODUCTIVE ISSUES
影响因子:
--
通讯作者:
Korach, Kenneth S.
Korach, Kenneth S.
中科院分区:
其他
文献类型:
--
作者:
Carpenter, Karen D.;Korach, Kenneth S.

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技术进步和新工具在阐明雌二醇和雌激素受体(ER)在生物过程中的作用方面取得了巨大进展,特别是在女性生殖系统中。多种遗传模型的开发和分析提供了对每个ER的特定功能的深入了解。本文综述了雌激素受体生物学在女性生殖的发展和使用的新型实验模型的见解。
Technological advances and new tools have brought about tremendous advances in elucidating the roles of estradiol and the estrogen receptors (ERs) in biological processes, especially within the female reproductive system. Development and analysis of multiple genetic models have provided insight into the particular functions of each of the ERs. This article reviews the insights into ER biology in female reproduction gained from the development and use of new types of experimental models.