Micro-arc oxidation of Ti6Al4V and Ti6Al7Nb alloys for biomedical applications
Micro-arc oxidation of Ti6Al4V and Ti6Al7Nb alloys for biomedical applications
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DOI：
10.1016/j.matchar.2011.01.002
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发表时间：
2011-03-01
影响因子：
4.7
通讯作者：
Sener, Cem
中科院分区：
文献类型：
--
作者：
Cimenoglu, Huseyin;Gunyuz, Mert;Sener, Cem
在本研究中，研究了两种竞争性钛合金（Ti6Al4V 和 Ti6Al7Nb）在相同电参数和暴露时间下，在含有电解质的 (CH3COO)(2)Ca 中心点 H2O 和 Na3PO4 中进行微弧氧化 (MAO) 工艺对其表面进行改性后的体外生物反应。处理后，合金表面覆盖一层厚（约 10 μm）的 TiO2 层，表现出不同的特性。 Ti6Al4V 合金的氧化物层是多孔的并且含有羟基磷灰石沉淀物，而Ti6Al7Nb 合金的氧化物层表现出更多的颗粒状外观并且含有钛酸钙沉淀物。进行模拟体液（SBF）和细胞培养测试来比较合金的生物学性能。尽管氧化合金在 SBF 测试中表现出有些相似的响应，但附着在 Ti6Al4V 合金氧化层上的 SAOS-2 细胞数量大于 Ti6Al7Nb 合金。 (C) 2011 Elsevier Inc. 保留所有权利。
In the present study, the in-vitro biological responses of two competitive titanium alloys (Ti6Al4V and Ti6Al7Nb) were investigated after modifying their surfaces by the micro-arc oxidation (MAO) process conducted in a (CH3COO)(2)Ca center dot H2O and Na3PO4 containing electrolyte under identical electrical parameters and exposure time. After the process, the surfaces of the alloys were covered with a thick (approx. 10 mu m) TiO2 layer exhibiting different characteristics. The oxide layer of the Ti6Al4V alloy was porous and contained hydroxyapatite precipitates whereas the oxide layer of the Ti6Al7Nb alloy showed a more grainy appearance and contained calcium titanate precipitates. Simulated body fluid (SBF) and cell culture tests were conducted to compare the biological performance of the alloys. Even though oxidized alloys exhibited somewhat similar response in SBF tests, the number of SAOS-2 cells attached to the oxide layer of the Ti6Al4V alloy was greater than that of the Ti6Al7Nb alloy. (C) 2011 Elsevier Inc. All rights reserved.