Letter by El Husseini et al regarding article, "What causes disability after transient ischemic attack and minor stroke?".
Letter by El Husseini et al regarding article, "What causes disability after transient ischemic attack and minor stroke?".
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El Husseini 等人关于文章“短暂性脑缺血发作和轻微中风后导致残疾的原因是什么？”的信函。
DOI：
10.1161/strokeaha.112.677708
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发表时间：
2012
期刊：
影响因子：
8.3
通讯作者：
Goldstein,LarryB
中科院分区：
文献类型：
--
作者：
ElHusseini,Nada;Laskowitz,DanielT;Zimmer,LouiseO;WilliamsJr,JohnW;Goldstein,LarryB
在CATCH研究结果的报告中，Coutts等人1惊讶地发现，15%的短暂性脑缺血发作（TIA）或轻微卒中受试者在90天时残疾（改良兰金评分> 2），并指出他们的研究“是新颖的，因为它强调了即使在轻微卒中中也需要检查残疾”。虽然目的和设计不同，但他们的数据与我们的研究一致，我们发现37%的TIA患者在事件发生后2 - 3个月的改良兰金评分>。2在我们的研究中，TIA患者致残的比例较高可能是由于研究人群和方法的差异，因为我们没有排除既往卒中/TIA患者。我们还发现，卒中患者（17.9%）与TIA患者（14.3%）3个月后抑郁的频率很高，并且出乎意料地相似。我们无法确定抑郁症在多大程度上可能导致功能障碍，导致它，或者是一个独立的现象。无论如何，我们同意Coutts等人的结论，但要补充的是，在经历TIA后，应评估患者的残疾和抑郁。
Reporting on the results of the CATCH study, Coutts et al1 were surprised that 15% of subjects with transient ischemic attack (TIA) or minor stroke were disabled (modified Rankin Score> 2) at 90 days and indicate that their study “is novel in that it emphasizes the need to examine disability even in minor stroke.” Although differing in purpose and design, their data are consistent with our study, in which we found 37% of patients with TIA had a modified Rankin Score> 2, 3 months after the event. 2 The higher proportion of TIA patients disabled in our study is likely attributable to differences in study populations and methodology because we did not exclude patients with previous stroke/TIA.We also found that the frequency of depression was high and unexpectedly similar after 3 months in patients who had a stroke (17.9%) versus TIA (14.3%). We could not determine the extent to which depression might have contributed to functional disability, resulted from it, or was an independent phenomenon. Regardless, we agree with Coutts et al1 conclusion, but would add that patients should be assessed for both disability and depression after experiencing a TIA.