Serious antibiotic-related adverse effects following unnecessary dental prophylaxis in the United States
Serious antibiotic-related adverse effects following unnecessary dental prophylaxis in the United States
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DOI：
10.1017/ice.2020.1261
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发表时间：
2021-01-01
影响因子：
4.5
通讯作者：
McGregor, Jessina C.
中科院分区：
文献类型：
--
作者：
Gross, Alan E.;Suda, Katie J.;McGregor, Jessina C.
方法我们使用 IBM Watson Health Marketscan 商业索赔/遭遇、医疗保险补充、福利协调研究数据库，对 2011 年至 2015 年间因看牙医而服用不必要的抗生素预防的患者进行了一项回顾性队列研究。参考 Suda、Calip 和 Zhou 2 如果患者参加了商业牙科保险并接受了不必要的抗生素预防，则纳入其中。抗生素预防的定义是在看牙医前 7 天内配发≤ 2 天的抗生素。排除抗生素预防前 14 天住院或口腔外感染的患者。不必要的抗生素预防被定义为对未接受牙龈或牙周手术且未进行适当的心脏诊断的患者进行预防。装有假体关节的患者被归类为不需要的患者（没有心脏病）。参考 Suda、Calip 和 Zhou 2 如果就诊间隔 > 7 天，则允许多次符合资格就诊的患者重新进入队列。
MethodsWe conducted a retrospective cohort study of patients prescribed unnecessary antibiotic prophylaxis for a dental visit between 2011 and 2015 using the IBM Watson Health Marketscan Commercial Claims/Encounters, Medicare Supplemental, Coordination of Benefits Research databases. Reference Suda, Calip and Zhou 2 Patients were included if they were enrolled in commercial dental insurance and received unnecessary antibiotic prophylaxis. Antibiotic prophylaxis was defined as a≤ 2 day supply of antibiotics dispensed within 7 days prior to a dental visit. Patients with a hospitalization or extra-oral infection 14 days prior to antibiotic prophylaxis were excluded. Unnecessary antibiotic prophylaxis was defined as prophylaxis in patients who did not undergo a procedure that manipulated the gingiva or tooth periapex and did not have an appropriate cardiac diagnosis. Patients with prosthetic joints were categorized as unnecessary (without a cardiac condition). Reference Suda, Calip and Zhou 2 Patients with multiple eligible visits were allowed to re-enter the cohort if visits were> 7 days apart.