Body mass index in relation to cardiovascular recovery from psychological stress among trauma-exposed women.
Body mass index in relation to cardiovascular recovery from psychological stress among trauma-exposed women.
复制标题
体重指数与遭受创伤的女性从心理压力中恢复心血管的关系。
DOI：
10.1007/s00406-019-01054-5
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发表时间：
2020
影响因子：
4.7
通讯作者：
Llabre,MariaM
中科院分区：
文献类型：
--
作者：
Kibler,JeffreyL;Ma,Mindy;Llabre,MariaM
延迟心血管恢复与更大的心脏病风险有关。然而，相对于应激反应，心血管恢复一直研究不足。此外，很少有研究审查了恢复与可能为促进恢复的努力提供信息的可变因素之间的联系。本研究的重点是身体质量指数（BMI）是否与恢复后的两个压力任务（语音和心算）。基于肥胖可能导致应激后恢复受损的概念，我们还研究了较高的BMI是否与先前报道的PTSD症状升高和延迟恢复之间的相关性有关。样本由50名19-49岁的创伤暴露平民妇女组成（M±SD = 30 ± 8）。压力任务之后是15分钟的任务后休息期。心血管恢复评估为恢复至基线的百分比;恢复指标包括心率（HR）、心输出量（CO）、收缩压（SBP）和舒张压（DBP）。PTSD严重程度基于结构化访谈。较高的BMI与言语任务的CO恢复显著减少和心算的HR恢复减少相关。较高的BMI与从数学任务中恢复的SBP更多相关，但与DBP恢复无关。基于Sobel中介检验，BMI在PTSD/CO恢复关系中的间接影响是显著的。这些结果部分支持了BMI与心血管恢复相关以及PTSD与恢复的关联可能由BMI介导的假设。
Delayed cardiovascular recovery has been associated with greater heart disease risks. However, relative to stress reactivity, cardiovascular recovery has been understudied. Further, few studies have examined associations of recovery with modifiable factors that might inform efforts to enhance recovery. The focus of the present study was whether body mass index (BMI) was associated with recovery following two stress tasks (speech and mental arithmetic). Based on the conceptualization that obesity may lead to impaired post-stress recovery, we also examined whether higher BMI accounted for previously reported associations between elevated PTSD symptoms and delayed recovery. The sample consisted of 50 trauma-exposed civilian women ages 19–49 (M±SD = 30 ± 8). The stress tasks were followed by 15-min post-task rest periods. Cardiovascular recovery was assessed as percentage return to baseline; the recovery measures consisted of heart rate (HR), cardiac output (CO), systolic blood pressure (SBP) and diastolic blood pressure (DBP). PTSD severity was based on structured interview. Higher BMI was associated with significantly less CO recovery from the speech task and less HR recovery from mental arithmetic. Higher BMI was associated with more SBP recovery from the math task, but was not associated with DBP recovery. The indirect effects of BMI in the PTSD/CO recovery relationship based on the Sobel test of mediation were significant. These results partially support the hypotheses that BMI is associated with cardiovascular recovery and that associations of PTSD with recovery may be mediated by BMI.