The implications of network structure for epidemic dynamics
The implications of network structure for epidemic dynamics
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DOI：
10.1016/j.tpb.2004.08.002
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发表时间：
2005-02-01
影响因子：
1.4
通讯作者：
Keeling, M
中科院分区：
文献类型：
--
作者：
Keeling, M
人们早就认识到，质量作用混合的标准假设是对控制感染传播的真正机械过程的粗略近似。特别是，许多感染可以被认为是通过有限的接触网络传播的。然而，尽管存在根本的差异，大规模行动模型仍在继续使用，并提供了对流行病行为的非常准确的描述。在这里，大规模行动和基于网络的模型之间的差异进行了研究。这使我们能够确定何时大规模行动模型是一个可靠的工具，并建议如何改进其行为。(C)2004年爱思唯尔公司All rights reserved.
It has long been realised that the standard assumptions of mass-action mixing are a crude approximation of the true mechanistic processes that govern the transmission of infection. In particular, many infections can be considered to be spread through a limited network of contacts. Yet, despite the underlying discrepancies, mass-action models continue to be used and provide a remarkably accurate description of epidemic behaviour. Here, the differences between mass-action and network-based models are investigated. This allows us to determine when mass-action models are a reliable tool, and suggest ways in which their behaviour should be refined. (C) 2004 Elsevier Inc. All rights reserved.