Perinatal stroke in term infants with neonatal encephalopathy

Perinatal stroke in term infants with neonatal encephalopathy
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DOI:
10.1212/01.wnl.0000129909.77753.c4
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发表时间:
2004-06-08
期刊:
影响因子:
9.9
通讯作者:
Ferriero, DM
Ferriero, DM
中科院分区:
医学1区
文献类型:
--
作者:
Ramaswamy, V;Miller, SP;Ferriero, DM

文献摘要

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在124名脑病足月婴儿的前瞻性队列中,有6名婴儿有急性局灶性中风。所有6名中风脑病患者均出现癫痫发作。所有6名患者在30个月时的神经发育结果都是异常的,与整个队列相比明显更差。这些发现表明,在患有脑病的新生儿中,急性局灶性中风是一种罕见但严重的事件,具有显著的神经发育异常结局的风险。
In a prospective cohort of 124 encephalopathic term infants, six infants had an acute focal stroke. All six encephalopathic patients with strokes presented with seizures. Neurodevelopmental outcome at 30 months was abnormal in all six patients and significantly worse when compared with the entire cohort overall. These findings suggest that in newborns with encephalopathy, acute focal strokes are an uncommon but serious occurrence with substantial risk for abnormal neurodevelopmental outcome.