Effect of exercise intensity on active and passive glucose absorption
Effect of exercise intensity on active and passive glucose absorption
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DOI：
10.1123/ijsnem.16.5.485
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发表时间：
2006-10-01
影响因子：
2.5
通讯作者：
Lambert, G. Patrick
中科院分区：
文献类型：
--
作者：
Lang, James A.;Gisolfi, Carl V.;Lambert, G. Patrick
本研究的目的是确定运动强度对主动和被动肠道葡萄糖吸收的影响。8名受过训练的跑步者（年龄= 23 +/- 2岁;最大摄氧量= 62.1 +/- 5.8 mL中心点kg（-1）中心点min（-1））在热中性环境中以30、50或70%VO2max进行了1小时的静息实验和3次1小时的跑台实验。在每次实验之前，水分充足的受试者立即摄入含有两种不可代谢的葡萄糖类似物3-O-甲基-D-葡萄糖（3 MG;主动吸收; 5g）和D-木糖（被动吸收; 5g）的溶液。在随后的5小时内，收集所有尿液，并测定尿液中3 MG和D-木糖的量。使用重复测量ANOVA，与其他强度相比，在70%VO2max下观察到每种碳水化合物的尿排泄显著减少（P < 0.05），表明在该强度下长时间跑步期间，葡萄糖的主动和被动肠道吸收都可能减少。
The purpose of this study was to determine the effects of exercise intensity on active and passive intestinal glucose absorption. Eight trained runners (age = 23 +/- 2 y; VO2max = 62.1 +/- 5.8 mL center dot kg(-1) center dot min(-1)) performed a 1 h resting experiment and three 1 h treadmill experiments at 30, 50, or 70% VO2max in a thermoneutral environment. Immediately prior to each experiment, euhydrated subjects ingested a solution containing two non-metabolizable glucose analogs, 3-O-methyl-D-glucose (3MG; actively absorbed; 5 g) and D-xylose (passively absorbed; 5 g). During the following 5 h, all urine was collected and the amount of 3MG and D-xylose in the urine was determined. Using repeated measures ANOVA, a significant (P < 0.05) reduction in urinary excretion of each carbohydrate was observed at 70% VO2max compared to the other intensities suggesting that both active and passive intestinal absorption of glucose may be reduced during prolonged running at this intensity.