Comparison between pernasal flocked swabs and nasopharyngeal aspirates for detection of common respiratory viruses in samples from children

Comparison between pernasal flocked swabs and nasopharyngeal aspirates for detection of common respiratory viruses in samples from children
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DOI:
10.1128/jcm.00369-08
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发表时间:
2008-07-01
影响因子:
9.4
通讯作者:
Hindiyeh, Musa Y.
Hindiyeh, Musa Y.
中科院分区:
医学2区
文献类型:
--
作者:
Abu-Diab, Afaf;Azzeh, Maysa;Hindiyeh, Musa Y.

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在这项前瞻性研究中,我们比较了使用经鼻植绒拭子样本与使用鼻咽抽吸物(NPA)样本检测455名5岁以下儿童的呼吸道病毒。总体而言,经鼻植绒拭子样本的灵敏度和特异性分别为98.5%和100%。植绒拭子样本的出色灵敏度与快速采集方法相结合,使其成为NPA样本的替代品,NPA样本的采集更具侵入性。
In this prospective study we compared the use of pernasal flocked swab samples with the use of nasopharyngeal aspirate (NPA) samples for the detection of respiratory viruses from 455 children less than 5 years of age. Overall, the sensitivity and the specificity of the pernasal flocked swab samples were 98.5% and 100%, respectively. The excellent sensitivity of the flocked swab samples in combination with the rapid means by which they may be collected makes them an alternative to NPA samples, whose collection is more invasive.