Assessment of muscle function in severely burned children
Assessment of muscle function in severely burned children
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DOI：
10.1016/j.burns.2007.10.006
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发表时间：
2008-06-01
期刊：
影响因子：
2.7
通讯作者：
Suman, Oscar E.
中科院分区：
文献类型：
--
作者：
Alloju, Shashi M.;Herndon, David N.;Suman, Oscar E.
简介：严重烧伤的创伤后反应导致明显和长期的骨骼肌分解代谢和虚弱，尽管标准的康复计划的职业和物理治疗持续存在。我们研究了严重烧伤后6个月骨骼肌分解代谢延长对儿童肌肉功能的影响程度。方法：烧伤儿童，烧伤面积约占体表面积的40%，在烧伤后6个月对其瘦体重和腿部肌肉力量进行评估。采用双能x线吸收仪评估瘦体重。用等速动力学法评估腿部肌肉力量。未烧伤的儿童进行了类似的评估，并作为对照。结果：我们发现严重烧伤儿童（n = 33）与未烧伤儿童（n = 46）相比，瘦体重明显降低。此外，他们的峰值扭矩和使用大腿伸肌的总工作性能都明显较低。结论：我们的研究结果为评估烧伤儿童的肌肉功能提供了客观和实用的临床方法，也有助于建立潜在的康复目标，并监测这些目标的进展。(c) 2007爱思唯尔有限公司和ISBI。版权所有。
Introduction: The posttraumatic response to a severe burn leads to marked and prolonged skeletal muscle catabolism and weakness, which persist despite standard rehabilitation programs of occupational and physical therapy. We investigated the degree to which the prolonged skeletal muscle catabolism affects the muscle function of children 6 months after severe burn.Methods: Burned children, with >40% total body surface area burned, were assessed at 6 months after burn in respect to lean body mass and leg muscle strength at 150%. Lean body mass was assessed using dual-energy X-ray absorptiometry. Leg muscle strength was assessed using isokinetic dynamometry. Nonburned children were assessed similarly, and served as controls.Results: We found that severely burned children (n = 33), relative to nonburned children (n = 46) had significantly lower lean body mass. Additionally they had significantly lower peak torque as well total work performance using the extensors of the thigh. Conclusions: Our results serve as an objective and a practical clinical approach for assessing muscle function and also aid in establishing potential rehabilitation goals, and monitoring progress towards these goals in burned children. (c) 2007 Elsevier Ltd and ISBI. All rights reserved.