Electrodermal Activity Moderates Sleep-Behavior Associations in Children with Autism Spectrum Disorder.
Electrodermal Activity Moderates Sleep-Behavior Associations in Children with Autism Spectrum Disorder.
复制标题
皮肤电活动调节自闭症谱系障碍儿童的睡眠行为关联。
DOI：
10.1007/s10802-022-00900-w
复制
发表时间：
2022
影响因子：
2.5
通讯作者：
Baker,JasonK
中科院分区：
文献类型：
--
作者：
Schiltz,HillaryK;Fenning,RachelM;Erath,StephenA;Baucom,BrianRW;Baker,JasonK
与没有自闭症谱系障碍（ASD）的儿童相比，患有自闭症谱系障碍的儿童会经历更多的睡眠问题，这可能会导致行为合并症。这项研究探索了心理生理学和睡眠之间的相互作用，以确定哪些自闭症儿童可能面临睡眠不足对白天行为的影响的风险，或者能够适应这种影响。参与者包括48名患有自闭症的儿童（6-10岁）。在基线和实验室挑战任务中收集交感神经系统活动（皮电活动；EDA）的测量。父母使用标准化问卷和临床访谈报告孩子的睡眠问题和行为功能，包括广泛的外化症状和情境性不服从。EDA调节了睡眠问题和两种行为结果之间的显著正相关。在基线EDA较低的情况下，睡眠问题与广泛的外化症状和情境不依从性之间的联系是积极和显著的，而在基线EDA较高的情况下则不显著。睡眠问题也与EDA反应相互作用，预测情境不服从，但不是广泛的外化症状。研究结果强调了自闭症儿童睡眠、日间行为和心理生理之间复杂的相互作用。结果是在不同易感性和双重风险框架的背景下解释的。这项研究强调了高质量睡眠对ASD儿童的重要性，特别是那些具有本研究确定的生物敏感性或易感因素（即EDA）的儿童。讨论了临床意义，并提出了今后的研究方向。
Relative to children without autism spectrum disorder (ASD), children with ASD experience elevated sleep problems that can contribute to behavioral comorbidities. This study explored the interaction between psychophysiology and sleep to determine which children with ASD may be at risk for, or resilient to, effects of poor sleep on daytime behavior. Participants included 48 children (aged 6–10 years) with ASD. Measures of sympathetic nervous system activity (electrodermal activity; EDA) were collected during a baseline and in response to a laboratory challenge task. Parents reported on their children’s sleep problems and behavioral functioning, including broad externalizing symptoms and situational noncompliance, using standardized questionnaires and a clinical interview. EDA moderated the significant positive associations between sleep problems and both behavioral outcomes. The link between sleep problems and broad externalizing symptoms and situational noncompliance was positive and significant in the context of lower baseline EDA and nonsignificant in the context of higher baseline EDA. Sleep problems also interacted with EDA reactivity in predicting situational noncompliance, but not broad externalizing symptoms. Findings highlight the complex interplay among sleep, daytime behavior, and psychophysiology in children with ASD. Results are interpreted in the context of differential susceptibility and dual-risk frameworks. This study underscores the importance of high-quality sleep for children with ASD, especially those with the biological sensitivity or vulnerability factors (i.e., EDA) identified in this study. Clinical implications are discussed, and directions for future research are provided.