Baicalin inhibits PDGF-BB-stimulated vascular smooth muscle cell proliferation through suppressing PDGFRβ-ERK signaling and increase in p27 accumulation and prevents injury-induced neointimal hyperplasia

Baicalin inhibits PDGF-BB-stimulated vascular smooth muscle cell proliferation through suppressing PDGFRβ-ERK signaling and increase in p27 accumulation and prevents injury-induced neointimal hyperplasia
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DOI:
10.1038/cr.2011.121
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发表时间:
2011
期刊:
影响因子:
44.1
通讯作者:
Li-Hua Dong;J. Wen;Sui‐bing Miao;Z. Jia;Hai‐juan Hu;Rong‐hua Sun;Yiling Wu;Mei Han
Li-Hua Dong;J. Wen;Sui‐bing Miao;Z. Jia;Hai‐juan Hu;Rong‐hua Sun;Yiling Wu;Mei Han
中科院分区:
生物学1区
文献类型:
--
作者:
Li-Hua Dong;J. Wen;Sui‐bing Miao;Z. Jia;Hai‐juan Hu;Rong‐hua Sun;Yiling Wu;Mei Han

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作者希望澄清我们最近发表在Cell Research(CR)(2010; 20:1252-1262)上的论文中的一个缺陷。我们没有参考我们之前在中国细胞生物学杂志(CJCB)上发表的关于黄芩苷对体外血管平滑肌细胞(VSMCs)影响的论文第一部分的结果。(2010; 32(1):91-96);重叠包括重新使用CJCB论文中的一些蛋白质印迹数据(包括图2D、3A和3C的上图中的那些;以及图5 B的ICAM-1和VCAM-1)。这些结果表明黄芩苷抑制PDGF-BB诱导的细胞增殖和迁移相关基因的表达,阻断细胞周期进程。我们,作者,理解,所有以前发表的材料应该承认,无论它以前发表在哪里;我们应该参考CJCB的文章,并获得许可,重新发表重叠的内容。我们为我们的疏忽向读者以及CR和CJCB表示诚挚的歉意。我们仍然相信,我们的CR文件已经对文献进行了有价值的补充,因为它汇集了
The authors would like to clarify a deficiency in our paper recently published in Cell Research (CR)(2010; 20: 1252-1262). We did not reference the results in the first part of our paper reporting the effect of baicalin on vascular smooth muscle cells (VSMCs) in vitro which we had previously published in the Chinese language only Chinese Journal of Cell Biology (CJCB)(2010; 32 (1): 91-96); the overlap includes the re-use of some western blot data from the CJCB paper (including those in upper panels of Figures 2D, 3A and 3C; and ICAM-1 and VCAM-1 of Figure 5B). These results suggest that baicalin inhibits PDGF-BB-induced expression of genes related to cell proliferation and migration, and blocks cell cycle progression.We, the authors, understand that all previously published material should be acknowledged no matter where it was previously published; we should have referenced the CJCB article and obtained permission to re-publish the overlapping content. We sincerely apologize to the readers and both CR and CJCB for our oversight. We remain confident that our CR paper has made a valuable addition to the literature as it brings together