Chronic Pain Has a Negative Impact on Sexuality in Testis Cancer Survivors
Chronic Pain Has a Negative Impact on Sexuality in Testis Cancer Survivors
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DOI：
10.2164/jandrol.110.012500
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发表时间：
2012-09-01
影响因子：
--
通讯作者：
Kliesch, Sabine
中科院分区：
文献类型：
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作者：
Puehse, Gerald;Wachsmuth, Julia Urte;Kliesch, Sabine
睾丸癌是一种直接影响男性阳刚之气的疾病，其治疗方法会损害性功能。本研究的目的是调查性功能障碍的患病率和慢性疼痛对长期睾丸癌幸存者性功能的影响。因此，我们检查了539例因睾丸生殖细胞肿瘤而切除了一个睾丸的患者。完成肿瘤治疗后，所有患者接受了详细的问卷调查，询问睾丸切除术前后睾丸疼痛的发生和临床表现。此外，节略版的国际勃起功能指数和简短性功能量表的项目被用来获得个人性功能的精确信息。总体而言，34.5%的睾丸癌幸存者抱怨性欲下降，41.6%的人性生活减少。高达31.5%的患者存在勃起功能障碍。24.4%的人在性交过程中保持勃起的能力受损。射精障碍（早泄、延迟、逆行或未射精）发生在84.9%的睾丸癌幸存者中。共有32.4%的参与者经历了性高潮强度的降低，95.4%的参与者经历了总体性满意度的降低。慢性疼痛症状的发生与勃起功能障碍、无法维持勃起、射精障碍和性高潮强度降低的相对频率和强度之间存在显著相关性。总之，慢性疼痛对睾丸癌幸存者的性行为有负面影响。
Testis cancer is a disease that directly affects a man's sense of masculinity and involves treatments compromising sexual function. The aim of this study was to investigate the prevalence of sexual dysfunction and the influence of chronic pain on sexuality in long-term testis cancer survivors. Thus, we examined 539 patients after they had one testis removed because of a testicular germ cell tumor. Having completed oncologic therapy, all patients received a detailed questionnaire asking about the occurrence and clinical presentation of testis pain before and after orchiectomy. In addition, items from the abridged International Index of Erectile Function and Brief Sexual Function Inventory were used to gain precise information on individual sexual function. Overall, 34.5% of our testicular cancer survivors complained of reduced sexual desire, and sexual activity was reduced in 41.6%. Erectile dysfunction was present in up to 31.5% of patients. In 24.4%, the ability to maintain an erection during intercourse was impaired. Ejaculatory disorders (premature, delayed, retrograde, or anejaculation) occurred in 84.9% of our testis cancer survivors. A total of 32.4% of our participants experienced a reduced intensity of orgasm, and 95.4% experienced reduced overall sexual satisfaction. There was a significant correlation between the occurrence of chronic pain symptoms and the relative frequency and intensity of erectile dysfunction, inability to maintain an erection, ejaculation disorders, and reduced intensity of orgasm. In conclusion, chronic pain has a negative impact on sexuality in testis cancer survivors.