Detection of thymine [2+2] photodimer repair in DNA: selective reaction of KMnO4.
Detection of thymine [2+2] photodimer repair in DNA: selective reaction of KMnO4.
复制标题
DNA 中胸腺嘧啶 [2 2] 光二聚体修复的检测：KMnO4 的选择性反应。
DOI：
10.1093/nar/26.17.3940
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发表时间：
1998
影响因子：
14.9
通讯作者：
Schuster,GB
中科院分区：
文献类型：
--
作者：
Ramaiah,D;Koch,T;Orum,H;Schuster,GB
利用高锰酸钾与单链DNA中胸腺嘧啶的特异性反应，分析了DNA和DNA/肽核酸杂交双链体中胸腺嘧啶[2+2]二聚体的修复。这种简单而高灵敏度的化学测定法便于监测寡核苷酸中胸腺嘧啶二聚体的修复。
The specific reaction of potassium permanganate with thymine in single-stranded DNA was employed to analyze thymine [2+2] dimer repair in DNA and in DNA/peptide nucleic acid hybrid duplexes. This simple and highly sensitive chemical assay is convenient for monitoring repair of thymine dimers in oligonucleotides.