Perspective: research highlights at the Case Western Reserve University Center for AIDS Research. Learning from the past and looking toward the future.

Perspective: research highlights at the Case Western Reserve University Center for AIDS Research. Learning from the past and looking toward the future.
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观点:凯斯西储大学艾滋病研究中心的研究亮点。

DOI:
10.1089/aid.1996.12.1659
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发表时间:
1996
期刊:
AIDS research and human retroviruses.
影响因子:
--
通讯作者:
Walker,CJ
Walker,CJ
中科院分区:
--
文献类型:
--
作者:
LeGrice,SF;Whalen,CC;Hom,DL;Lehmann,PV;Walker,CJ

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1994年,凯斯西储大学(CWRU)艾滋病研究中心(CFAR)将其在国际艾滋病和分支杆菌研究方面的长期优势与分子生物学和免疫学计划结合起来,解决艾滋病疫苗的开发、诊断和化疗问题。这些努力的一个关键组成部分是设施的可用性,以评估基础研究进展的临床益处,以及为正在进行的研究计划提供样本。在CWRU,这是通过其CFAR和艾滋病临床试验单位(ACTU)之间富有成效的合作实现的。总体而言,这些努力为CWRU和克利夫兰临床基金会研究所的临床医生和科学家提供了一个互动的氛围,其结果在这里简要强调。
Fundedin 1994, the Center for AIDS Research (CFAR) at Case Western Reserve University (CWRU) combines its long-standing strengths in international AIDS and mycobacte-rial research with programs of molecular biology and im-munology to address issues of AIDS vaccine development, di-agnosis and chemotherapy. A critical component of these efforts is the availability of facilities to evaluate the clinical benefit of advances in basic research, as well as to provide specimens for ongoing research programs. At CWRU, this has been achieved through a productive collaboration between its' CFAR and AIDS Clinical Trials Unit (ACTU). Collectively, these efforts provide an interactive atmosphere for clinicians and scientists at CWRU and the Research Institute of the Cleveland Clinic Foundation, the results of which are briefly highlighted here.
劳斯肉瘤病毒和人类免疫缺陷病毒 1 蛋白酶底物结合袋的突变分析。
DOI: --
发表时间: 1994
期刊: The Journal of biological chemistry
影响因子: --
作者:
Cameron,CE;Ridky,TW;Shulenin,S;Leis,J;Weber,IT;Copeland,T;Wlodawer,A;Burstein,H;Bizub-Bender,D;Skalka,AM
通讯作者: Skalka,AM
作为潜在疫苗的非复制病毒载体:表达麻疹病毒融合(F)和血凝素(HA)糖蛋白的重组金丝雀痘病毒。
DOI: --
发表时间: 1992
期刊: Virology
影响因子: 3.7
作者:
Jill Taylor;R. Weinberg;J. Tartaglia;C. Richardson;C. Richardson;G. Alkhatib;D. Briedis;M. Appel;E. Norton;E. Paoletti
通讯作者: E. Paoletti
对过敏性鼻炎和临床耐受个体中人 IL-4 和 IFN-γ 产生的过敏原驱动的有限稀释分析。
DOI: 10.1093/intimm/8.6.897
发表时间: 1996
影响因子: 4.4
作者:
Y. Li;F. Simons;F. Jay;K. HayGlass
通讯作者: K. HayGlass
用表达狂犬病糖蛋白的金丝雀痘病毒进行免疫
DOI: --
发表时间: 1992
期刊: The Lancet
影响因子: --
作者:
M. Cadoz;B. Meignier;S. Plotkin;A. Strady;J. Taylor;J. Tartaglia;E. Paoletti
通讯作者: E. Paoletti
DOI: 10.1172/jci117611
发表时间: 1994-12-01
影响因子: 15.9
作者:
ZHANG, M;GONG, JH;BARNES, PF
通讯作者: BARNES, PF