Interactive effect of BCL2 and BAX polymorphisms with cigarette smoking on the risk of non-small cell lung cancer: a case–control study in China
Interactive effect of BCL2 and BAX polymorphisms with cigarette smoking on the risk of non-small cell lung cancer: a case–control study in China
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DOI：
10.1093/abbs/gmz103
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发表时间：
2019
影响因子：
3.7
通讯作者：
Cai Yanlin
中科院分区：
文献类型：
--
作者：
Jiang Pei;Tang Jianxin;Shao Qiong;Cai Yanlin
Lung cancer, predominantly non-small cell lung cancer (NSCLC), is a deadly disease with a 5-year survival rate of <15%. A number of environmental and genetic risk factors for lung cancer have been identified. Cigarette smoking is a well-recognized risk factor for lung cancer. Approximately 85% of lung cancers are caused by cigarette smoking. Epidemiological studies suggested an association of NSCLC with genetic susceptibility in the general population, and a recent study suggested that genetic polymorphisms in apoptotic pathway genes may attribute partly to this predisposition [1].
