Major plasma lipids and fatty acids in four HDL mammals
Major plasma lipids and fatty acids in four HDL mammals
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DOI：
10.1016/s1095-6433(02)00031-4
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发表时间：
2002-06-01
影响因子：
2.3
通讯作者：
Aveldaño, MI
中科院分区：
文献类型：
--
作者：
Maldonado, EN;Casanave, EB;Aveldaño, MI
脂质类和它们的脂肪酸进行了比较，血浆中的四种哺乳动物：实验室啮齿动物，小鼠;两个家养动物，猫和狗;和野生动物，南美犰狳，毛鞭。总的来说，最丰富的脂蛋白是高密度脂蛋白（HDL）。在血浆总脂质中，磷脂（PL）在所有四个物种中占主导地位，与HDL的比例相关，两者在犬中均最大。磷脂主要为磷脂酰胆碱（PC），其次为鞘磷脂（SM）和溶血磷脂酰胆碱。从四个物种的总血浆脂质含有长链n-6多不饱和脂肪酸作为主要的酰基，其次是相当比例的总饱和和单烯脂肪酸和小百分比的n-3多不饱和脂肪酸。PC，SM，三酰甘油和胆固醇酯中这四个主要脂肪酸组的百分比在物种之间是相似的，但组成这些组的主要单个脂肪酸之间的比率显示出显着差异。(C)2002年爱思唯尔科技有限公司All rights reserved.
Lipid classes and their fatty acids were compared in plasma from four mammals: a laboratory rodent, the mouse; two domestic animals, the cat and dog; and a wild animal, the South American armadillo, Chaetophractus villosus. In all, the most abundant lipoprotein was high-density lipoprotein (HDL). In the total lipid of plasma, phospholipids (PL) predominated in all four species, in correlation with the proportion of HDL, both being largest in dogs. The major PL was phosphatidylcholine (PC), followed by sphingomyelin (SM) and lysophosphatidylcholine. The total plasma lipid from the four species contained long-chain n-6 polyunsaturated fatty acids as the predominant acyl groups, followed by comparable proportions of total saturated and monoenoic fatty acids and small percentages of n-3 PUFA. The percentages of these four major groups of fatty acids in PC, SM, triacylglycerols and cholesterol esters were similar among species, but showed significant differences in the ratios between major individual fatty acids composing these groups. (C) 2002 Elsevier Science Inc. All rights reserved.