Bladder activation by selective stimulation of pudendal nerve afferents in the cat
Bladder activation by selective stimulation of pudendal nerve afferents in the cat
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DOI：
10.1016/j.expneurol.2008.04.010
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发表时间：
2008-07-01
影响因子：
5.3
通讯作者：
Grill, Warren M.
中科院分区：
文献类型：
--
作者：
Yoo, Paul B.;Woock, John P.;Grill, Warren M.
脊髓完整猫和脊髓横断猫的阴部神经刺激引起的膀胱收缩支持慢性脊髓损伤(SCI)患者恢复尿路功能的可能性。然而，脊髓损伤患者的电诱发膀胱反应仅限于相对较低压力下的短暂收缩。这促使了本研究，该研究详细量化了在不同刺激频率下选择性刺激阴部神经个别分支所引起的反应。在用α-氯醛糖麻醉的完整脊髓猫中，选择性频率依赖的感觉电激活(2赫兹)
Bladder contractions evoked by pudendal nerve stimulation in both spinal intact and spinal transected cats support the possibility of restoring urinary function in persons with chronic spinal cord injury (SCI). However, electrically evoked bladder responses in persons with SCI were limited to transient contractions at relatively low pressures. This prompted the present study, which presents a detailed quantification of the responses evoked by selective stimulation of individual branches of the pudendal nerve at different stimulation frequencies. In spinal intact cats anesthetized with alpha-chloralose, selective frequency-dependent electrical activation of the sensory (2 Hz