Investigation of Adsorptive Orientation State Change of Anionic Porphyrin with Hydrolysis Reaction of α-Tricalcium Phosphate
Investigation of Adsorptive Orientation State Change of Anionic Porphyrin with Hydrolysis Reaction of α-Tricalcium Phosphate
复制标题
α-磷酸三钙水解反应阴离子卟啉吸附取向态变化的研究
DOI：
10.1039/d2ce00505k
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发表时间：
2022
期刊：
影响因子：
3.1
通讯作者：
Motohiro Tagaya
中科院分区：
文献类型：
--
作者：
Daichi Noda;Norio Saito;Iori Yamada;Motohiro Tagaya
本文研究了α，β，γ，δ-四（4-羧基苯基）卟啉（TCPP）与α-磷酸三钙水解生成的羟基磷灰石（HA）微晶之间的界面相互作用。吸附在HA表面的TCPP的光吸收光谱显示，TCPP是有利的垂直排列在HA核表面，然后其取向改变为水平的水解反应进行。TCPP分子取向与HA的洗脱、成核和晶体生长过程敏感相关，因此可通过水解反应时间进行控制。本研究首次报道了磷酸钙-卟啉相互作用变化的界面行为，并提出了在生物陶瓷表面组织有序分子组装的新概念。
We herein investigated the interfacial interactions between α,β,γ,δ-tetrakis(4-carboxyphenyl)porphyrin (TCPP) and the hydroxyapatite (HA) crystallite converted via hydrolysis reaction from α-tricalcium phosphate. Photoabsorption spectroscopy of the TCPP adsorbed on the HA surfaces revealed that TCPP was favorably vertically arranged on the HA nuclei surface, and then its orientation was changed to be horizontal as the hydrolysis reaction progressed. The TCPP molecular orientation was sensitively associated with elution, nucleation, and crystal growth processes of HA and thus was controllable by the hydrolysis reaction time. The present study is the first report for further understanding of the interfacial behavior of the calcium phosphate–porphyrin interactive changes and also proposes a new concept to organize a well-arranged molecular assembly on bioceramic surfaces.