The parahippocampal gyrus in the baboon:: Anatomical, cytoarchitectonic and magnetic resonance imaging (MRI) studies
The parahippocampal gyrus in the baboon:: Anatomical, cytoarchitectonic and magnetic resonance imaging (MRI) studies
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DOI：
10.1093/cercor/bhg123
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发表时间：
2004-03-01
期刊：
影响因子：
3.7
通讯作者：
Insausti, R
中科院分区：
文献类型：
--
作者：
Blaizot, X;Martinez-Marcos, A;Insausti, R
海马旁回位于内侧颞叶，是陈述性记忆加工的关键结构。我们分析了狒狒海马旁回的一般组织，狒狒是一种与人类相对接近的非人灵长类动物。该区域由颞极、嗅周、嗅内（分为七个亚区）和海马旁后部（TH区和TF区）皮层向东组成。在三个大脑中进行了基本分析，连续切片并用硫蛋白、髓磷脂染色、乙酰胆碱酯酶和小白蛋白染色，以确定细胞结构边界。将所有子场的边界绘制在透明相机图上，并绘制海马旁回表面和地形的二维图。最后，将每个海马体旁区的界限转移到两只动物的相应MR图像上（通常用于体内PET或功能性MRI激活研究），以进行精确识别。狒狒海马旁回的一般细胞结构特征与猕猴相似，但颞极皮层的大小以及周围和后海马旁皮层的层状组织更像人类而不是猕猴。综上所述，狒狒海马旁皮层的大小和结构使得该物种非常适合用于记忆功能的实验研究。
The parahippocampal gyrus, located at the medial temporal lobe, is a key structure in declarative memory processing. We have analyzed the general organization of the parahippocampal gyrus in the baboon, a nonhuman primate species relatively close to human. This region is rostrocaudally made up of the temporopolar, perirhinal, entorhinal (divided into seven subfields) and posterior parahippocampal (areas TH and TF) cortices. The basic analysis has been performed in three brains, serially sectioned and stained with thionin, myelin stain, acetylcholinesterase and parvalbumin, to determine cytoarchitectonic boundaries. Borders of all subfields were charted onto camera lucida drawings, and two-dimensional maps of the surface and topography of the parahippocampal gyrus were made. Finally, the limits of each parahippocampal area were then transposed on corresponding MR images (commonly used for in vivo PET or functional MRI activation studies) of two animals for precise identification. The general cytoarchitectonic features of the baboon parahippocampal gyrus are similar to macaques, but the size of temporopolar cortex and the laminar organization of perirhinal and posterior parahippocampal cortices resemble humans more than macaque species. In conclusion, the size and structure of the baboon parahippocampal cortex makes this species very appropriate for experimental studies on memory function.