Investigating the Effectiveness of Current and Modified World Health Organization Guidelines for the Control of Soil-Transmitted Helminth Infections
Investigating the Effectiveness of Current and Modified World Health Organization Guidelines for the Control of Soil-Transmitted Helminth Infections
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DOI：
10.1093/cid/ciy002
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发表时间：
2018-06-15
影响因子：
11.8
通讯作者：
Anderson, Roy M.
中科院分区：
文献类型：
--
作者：
Farrell, Sam H.;Coffeng, Luc E.;Anderson, Roy M.
背景为了更好地了解大规模预防性化疗治疗对控制土源性蠕虫（STH）感染引起的发病率的有效性，已经做出了相当大的努力：蛔虫、鞭虫和2种钩虫，美洲钩虫和钩虫。目前世界卫生组织（WHO）的STH控制指南包括基于患病率测量的大规模药物管理（MDA）计划，旨在通过降低中度至重度感染的患病率，
Background. Considerable efforts have been made to better understand the effectiveness of large-scale preventive chemotherapy therapy for the control of morbidity caused by infection with soil-transmitted helminths (STHs): Ascaris lumbricoides, Trichuris trichiura, and the 2 hookworm species, Necator americanus and Ancylostoma duodenale. Current World Health Organization (WHO) guidelines for STH control include mass drug administration (MDA) programs based on prevalence measurements, aiming at reducing morbidity in pre-school-aged children (pre-SAC) and school-aged children (SAC) by lowering the prevalence of moderate- to heavy-intensity infections to