Noninvasive Observations of Peripheral Angle in Eyes After Penetrating Keratoplasty Using Anterior Segment Fourier-Domain Optical Coherence Tomography
Noninvasive Observations of Peripheral Angle in Eyes After Penetrating Keratoplasty Using Anterior Segment Fourier-Domain Optical Coherence Tomography
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DOI：
10.1097/ico.0b013e318226daa9
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发表时间：
2012-03-01
期刊：
影响因子：
2.8
通讯作者：
Araie, Makoto
中科院分区：
文献类型：
--
作者：
Fukuda, Reina;Usui, Tomohiko;Araie, Makoto
目的：应用前节傅里叶域光学相干断层扫描（OCT）研究穿透性角膜移植术（PKP）患者虹膜小梁接触（ITC）是否为周围性前粘连（PAS）。方法：回顾性观察性病例系列。采用市售前节傅里叶域OCT系统（CASIA； TOMEY，名古屋，日本）的角度分析模式，计算在东京大学医院眼科行PKP的52例患者60只眼的ITC、ITC指数和ITC面积（平均术后随访时间102.8 +/- 116.1个月）。我们与术前诊断、晶状体状态、手术方式、手术频率、移植物大小、眼压升高等因素分析ITC的发生、ITC指数、ITC面积。结果：60眼中28眼（46.7%）出现ITC。平均ITC指数14.0%，平均ITC面积5.97 mm(2)。ITC与大疱性角膜病变、感染性角膜炎、假性晶状体、PKP合并白内障手术、多次PKP手术和大移植物尺寸显著相关。结论：前段傅里叶域OCT是一种有用的创新工具，可以观察前房角，检查ITC作为角膜混浊的PAS，即使在PKP后也是如此。
Purpose: To examine iridotrabecular contact (ITC) as a peripheral anterior synechia (PAS) of patients who underwent penetrating keratoplasty (PKP) using anterior segment Fourier-domain optical coherence tomography (OCT).Methods: Retrospective, observational case series. ITC, ITC index, and ITC area of 60 eyes of 52 patients who underwent PKP at the Department of Ophthalmology in the University of Tokyo Hospital (mean follow-up time 102.8 +/- 116.1 months postoperation) were calculated using the angle analysis mode of a commercially available anterior segment Fourier-domain OCT system (CASIA; TOMEY, Nagoya, Japan). We analyzed the occurrence of ITC, ITC index, and ITC area with preoperative diagnosis, lens status, operation method, operation frequency, graft size, and intraocular pressure elevation.Results: ITC was observed in 28 (46.7%) of 60 eyes. Average ITC index was 14.0%, and average ITC area was 5.97 mm(2). ITC was significantly associated with eyes with bullous keratopathy, infectious keratitis, pseudophakia, PKP with cataract operation, several PKP operations, and large graft size.Conclusions: Anterior segment Fourier-domain OCT is a useful and innovative tool that enables us to observe the anterior chamber angle and examine ITC as PAS of eyes with corneal opacity, even after PKP.