Hydrosilane reduction of tertiary carboxamides by iron carbonyl catalysts.
Hydrosilane reduction of tertiary carboxamides by iron carbonyl catalysts.
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DOI：
10.1002/anie.200905025
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发表时间：
2009-12
影响因子：
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通讯作者：
Y. Sunada;H. Kawakami;Tsuyoshi Imaoka;Yukihiro Motoyama;H. Nagashima
中科院分区：
文献类型：
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作者：
Y. Sunada;H. Kawakami;Tsuyoshi Imaoka;Yukihiro Motoyama;H. Nagashima
羧胺中的Fox：叔羧胺以[Fe (CO) 5]或[Fe 3 (CO) 12]为还原剂，以1,1,3,3四甲基硅氧烷（TMDS）为还原剂，催化还原为相应的胺。反应在热或光化学条件下进行。与使用铂或钌催化剂还原酰胺的氢硅烷不同，TMDS优先还原硝基，即使在竞争酰胺存在的情况下。
Fox in the carboxamide: Reduction of tertiary carboxamides to their corresponding amines is catalyzed by [Fe (CO) 5] or [Fe 3 (CO) 12], using 1, 1, 3, 3tetramethyldlsiloxane (TMDS) as the reducing agent. The reaction proceeds under either thermal or photochemical conditions. Unlike the hydrosilane reduction of amides using platinum or ruthenlum catalysts, TMDS preferentially reduces a nitro group, even in the presence of competing amides.