An Mrp-Like Cluster in the Halotolerant Cyanobacterium Aphanothece halophytica Functions as a Na+/H+ Antiporter
An Mrp-Like Cluster in the Halotolerant Cyanobacterium Aphanothece halophytica Functions as a Na+/H+ Antiporter
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DOI：
10.1128/aem.01387-09
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发表时间：
2009-10-15
影响因子：
4.4
通讯作者：
Takabe, Teruhiro
中科院分区：
文献类型：
--
作者：
Fukaya, Fuminori;Promden, Worrawat;Takabe, Teruhiro
mrp同源基因簇mrpCD 1D 2 EFGAB（Ap-mrp）被发现在耐盐蓝藻，Aphanothece盐生隐杆藻，扩增，并在大肠杆菌突变体TO 114中表达。Ap-mrp与TO 114的盐敏感表型互补，具有Na+/H+和Li+/H+交换活性，表明Ap-mrp具有Na+/H+逆向转运蛋白的功能。
The mrp homolog gene cluster mrpCD1D2EFGAB (Ap-mrp) was found in a halotolerant cyanobacterium, Aphanothece halophytica, amplified, and expressed in Escherichia coli mutant TO114. Ap-mrp complemented the salt-sensitive phenotype of TO114 and exhibited Na+/H+ and Li+/H+ exchange activities, indicating that Ap-Mrp functions as a Na+/H+ antiporter.