Recruitment and retention of elderly patients in clinical trials -: Issues and strategies

Recruitment and retention of elderly patients in clinical trials -: Issues and strategies
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DOI:
10.1176/appi.ajgp.9.2.136
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发表时间:
2001-03-01
影响因子:
7.2
通讯作者:
Sheikh, JI
Sheikh, JI
中科院分区:
医学1区
文献类型:
--
作者:
Cassidy, EL;Baird, E;Sheikh, JI

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临床医生和研究人员都在将他们的重点放在老年患者身上,以便针对各种精神疾病进行最有效的治疗。对老年患者进行临床试验是必要的,因为他们使用的处方药数量最多。在设计和构建临床研究时有特殊的挑战和考虑。作者回顾了这类研究的各个阶段,包括招募合适的患者和保留入选的患者,并利用已经完成的研究研究的例子提出建议,说明被发现是成功的方法。
Clinicians and researchers alike are shifting their focus to elderly patients to elderly patients in order to target the most effective treatments for a variety of psychiatric conditions. Clinical trials with elderly patients are the necessary because they consume the largest number of prescription medications. There are special challenges and considerations in designing and constructing clinical studies. The authors review the various phases of such research, including recruitment of appropriate patients and retention of those enrolled, and they make suggestions, using examples from already completed research studies, illustrating the methods found to be successful.