Knowledge and Awareness of Human Papillomavirus (HPV), Cervical Cancer and HPV Vaccine among Women in Two Distinct Nepali Communities
Knowledge and Awareness of Human Papillomavirus (HPV), Cervical Cancer and HPV Vaccine among Women in Two Distinct Nepali Communities
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DOI：
10.7314/apjcp.2014.15.19.8287
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发表时间：
2014-01-01
影响因子：
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通讯作者：
Shrestha, Sadeep
中科院分区：
文献类型：
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作者：
Johnson, Derek Christopher;Bhatta, Madhav Prasad;Shrestha, Sadeep
背景：本研究评估了尼泊尔两个亚人群中女性对人乳头瘤病毒 (HPV)、宫颈癌和 HPV 疫苗的了解和认识——Khokana 是位于加德满都以南约 8 公里的拉利特布尔地区的一个传统 Newari 村庄，以及 Sanphebagar 是尼泊尔远西部农村地区 Achham 地区的一个村庄发展委员会。方法：研究参与者是在尼泊尔非政府组织尼泊尔生育护理中心举办的健康营期间招募的。经验丰富的工作人员管理了尼泊尔语调查工具，其中包括有关社会人口统计、生殖健康以及 HPV、宫颈癌和 HPV 疫苗知识的问题。结果：749 名参与者中，387 名（51.7%）来自科卡纳，362 名（48.3%）来自桑菲巴加尔。总体而言，53.3% (n=372) 的女性了解宫颈癌，Khokana 和 Sanphebagar 之间存在显着差异（63.3% vs 43.0%；p=0.001）。总体而言，15.4% (n=107) 的女性听说过 HPV，其中 32% (n=34) 的女性报告听说过 HPV 疫苗。如果免费的话，77.5% 的女性表示愿意让她们的孩子接种 HPV 疫苗。与宫颈癌认知相关的因素包括对 HPV 的了解（Khokana：比值比 (OR)=24.5；（95% 置信区间 (CI)：3.1-190.2，Sanphebagar：OR=14.8；95% CI：3.7-58.4））和性传播感染知识（Khokana：OR=6.18；95% CI： 3.1-12.4；Sanphebagar：OR=17.0；95% CI：7.339.7）以及其他危险因素。结论：Khokana 和 Sanphebagar 的女性对 HPV、宫颈癌和 HPV 疫苗的了解和认识仍然较低。对儿童免费提供的 HPV 疫苗的接受度很高，表明这些社区的潜在接种率很高。
Background: This study assessed human papillomavirus (HPV), cervical cancer, and HPV vaccine knowledge and awareness among women in two sub-populations in Nepal -Khokana, a traditional Newari village in the Lalitpur District about eight kilometers south of Kathmandu, and Sanphebagar, a village development committee within Achham District in rural Far-Western Nepal. Methods: Study participants were recruited during health camps conducted by Nepal Fertility Care Center, a Nepali non-governmental organization. Experienced staff administered a Nepali language survey instrument that included questions on socio-demographics, reproductive health and knowledge on HPV, cervical cancer, and the HPV vaccine. Results: Of the 749 participants, 387 (51.7%) were from Khokana and 362 (48.3%) were from Sanphebagar. Overall, 53.3% (n=372) of women were aware of cervical cancer with a significant difference between Khokana and Sanphebagar (63.3% vs 43.0%; p=0.001). Overall, 15.4% (n=107) of women had heard of HPV and 32% (n=34) of these women reported having heard of the HPV vaccine. If freely available, 77.5% of the women reported willingness to have their children vaccinated against HPV. Factors associated with cervical cancer awareness included knowledge of HPV (Khokana: Odds Ratio (OR)=24.5; (95% Confidence Interval (CI): 3.1-190.2, Sanphebagar: OR=14.8; 95% CI: 3.7-58.4)) and sexually transmitted infections (Khokana: OR=6.18; 95% CI: 3.1-12.4; Sanphebagar: OR=17.0; 95% CI: 7.339.7) among other risk factors. Conclusions: Knowledge and awareness of HPV, cervical cancer, and the HPV vaccine remains low among women in Khokana and Sanphebagar. Acceptance of a freely available HPV vaccine for children was high, indicating potentially high uptake rates in these communities.