Pulmonary Arterial Hypertension Baseline Characteristics From the REVEAL Registry

Pulmonary Arterial Hypertension Baseline Characteristics From the REVEAL Registry
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DOI:
10.1378/chest.09-1140
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发表时间:
2010-02-01
期刊:
影响因子:
9.6
通讯作者:
McGoon, Michael D.
McGoon, Michael D.
中科院分区:
医学1区
文献类型:
--
作者:
Badesch, David B.;Raskob, Gary E.;McGoon, Michael D.

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背景:建立评估早期和长期肺动脉高压疾病管理的登记处(REVEAL登记处)的目的是提供肺动脉高压(PAH)患者的最新特征,并改善诊断、治疗和管理。方法:54个美国中心连续招募了世界卫生组织I组PAR患者,这些患者符合扩展血流动力学标准:静息时平均肺动脉压(PAP)> 25毫米汞柱(运动时为30毫米汞柱),肺动脉高压毛细管楔压 (PCWP) = 240 dynes.s.cm(-5)。符合传统血流动力学定义的患者(PCWP
Background: The Registry to EValuate Early And Long-term pulmonary arterial hypertension disease management (REVEAL Registry) was established to provide updated characteristics of patients with pulmonary arterial hypertension (PAH) and to improve diagnosis, treatment, and management.Methods: Fifty-four US centers enrolled consecutively screened patients with World Health Organization group I PAR who met expanded hemodynamic criteria of mean pulmonary arterial pressure (PAP) > 25 mm Hg at rest (30 mm Hg with exercise), pulmonary capillary wedge pressure (PCWP) = 240 dynes.s.cm(-5). Patients meeting the traditional hemodynamic definition (PCWP