Detection of unexpected events during spatial navigation in humans: bottom-up attentional system and neural mechanisms
Detection of unexpected events during spatial navigation in humans: bottom-up attentional system and neural mechanisms
复制标题
DOI：
10.1111/j.1460-9568.2008.06060.x
复制
发表时间：
2008-02-01
影响因子：
3.4
通讯作者：
Barton, Jason J. S.
中科院分区：
文献类型：
--
作者：
Iaria, Giuseppe;Fox, Christopher J.;Barton, Jason J. S.
导航是一种复杂的认知能力，需要对从环境中提取的几种不同类型的信息进行处理和整合。然而，在导航时，可能会突然发生意外事件，个人需要迅速发现这些事件，以便应用适当的行为反应。对于检测意外事件不可或缺的警报机制被称为自下而上的注意系统。利用事件相关功能磁共振成像，我们研究了当个体在虚拟环境中移动时，自下而上检测意外事件的神经基础。当我们在这个虚拟环境中导航时，我们确定了右额-颞-顶网络中对意外事件的反应的激活。此外，当意外事件需要调整的行为反应时，右侧腹外侧额前皮质的一个区域(区域45和47/12)被选择性地激活。我们的数据重复了早期关于视觉注意背后的神经机制的发现，并将这些发现扩展到更复杂的现实生活中的空间导航能力，从而表明这些神经机制有助于自下而上的注意系统，而自下而上的注意系统对于真实环境中的有效运动至关重要。
Navigation is a complex cognitive ability requiring the processing and integration of several different types of information extracted from the environment. While navigating, however, an unexpected event may suddenly occur, which individuals are required to detect promptly in order to apply an appropriate behavioural response. The alerting mechanism that is integral to the detection of unexpected events is referred to as the bottom-up attentional system. Using event-related functional magnetic resonance imaging, we investigated the neural basis of bottom-up detection of unexpected events while individuals moved within a virtual environment. We identified activation within a right fronto-temporo-parietal network in response to unexpected events while navigating in this virtual environment. Furthermore, when an unexpected event requires an adjusted behavioural response, a region of the right ventrolateral pre-frontal cortex (areas 45 and 47/12) is selectively activated. Our data replicate earlier findings on the neural mechanisms underlying visual attention and extend these findings to the more complex real-life ability of spatial navigation, thereby suggesting that these neural mechanisms subserve the bottom-up attentional systems that are crucial for effective locomotion in real surroundings.