Experimental hemiballismus in the baboon produced by injection of a gamma-aminobutyric acid antagonist into the basal ganglia
Experimental hemiballismus in the baboon produced by injection of a gamma-aminobutyric acid antagonist into the basal ganglia
复制标题
狒狒基底神经节注射γ-氨基丁酸拮抗剂产生实验性偏侧投掷
DOI：
10.1016/0304-3940(80)90176-7
复制
发表时间：
1980
影响因子：
2.5
通讯作者：
A. Jackson
中科院分区：
文献类型：
--
作者：
A. Crossman;M. Sambrook;A. Jackson
通过将γ-氨基丁酸（GABA）拮抗剂印防己毒素注射到有意识的动物的苍白球/丘脑底核中，在狒狒身上实验性地产生了偏侧投掷症。异常运动出现在注射侧对侧的肢体中，其特征与丘脑底核损伤后报道的相似。
Hemiballismus was produced experimentally in the baboon by injection of the gamma-aminobutyric acid (GABA) antagonist picrotoxin into the globus pallidus/subthalamic nucleus of the conscious animal. The abnormal movements appeared in the limbs contralateral to the injected side and were of a character similar to those reported following lesions of the subthalamic nucleus.