DISSOCIATION BETWEEN BEHAVIORAL AND CORTICOSTERONE RESPONSES ON REPEATED EXPOSURES TO CAT ODOR
DISSOCIATION BETWEEN BEHAVIORAL AND CORTICOSTERONE RESPONSES ON REPEATED EXPOSURES TO CAT ODOR
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DOI：
10.1016/0031-9384(93)90333-b
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发表时间：
1993-12-01
影响因子：
2.9
通讯作者：
MABBUTT, PS
中科院分区：
文献类型：
--
作者：
FILE, SE;ZANGROSSI, H;MABBUTT, PS
暴露于恐惧刺激（猫的气味）5分钟的老鼠的血浆皮质酮浓度显着高于暴露于中性气味的老鼠以及动物舍中未受干扰的老鼠。在第一次接触猫气味期间，皮质酮的增加与回避行为有关，以躲避的时间来衡量。在五次接触猫气味后，老鼠继续避开气味布，但不再出现皮质酮水平升高的反应。研究结果是根据恐惧反应的两个组成部分（回避和干扰）进行讨论的，并且表明，通过皮质酮的变化反映的后者比前者更容易习惯。
Rats exposed for 5 min to a phobic stimulus (the odor of a cat) had plasma corticosterone concentrations significantly higher than those exposed to a neutral odor and than a group remaining undisturbed in the animal house. During the first exposure to cat odor the increased corticosterone was related to the avoidance behavior, measured as the time spent sheltering. After five exposures to cat odor the rats continued to avoid the odor cloth, but no longer responded with raised corticosterone levels. The results are discussed with reference to the two components of a phobic response (avoidance and disturbance), and it is suggested that the latter, reflected by changes in corticosterone, habituates more readily than the former.