ALTERATIONS IN THE MECHANICAL-PROPERTIES OF PERIPHERAL-NERVE FOLLOWING CRUSH INJURY
ALTERATIONS IN THE MECHANICAL-PROPERTIES OF PERIPHERAL-NERVE FOLLOWING CRUSH INJURY
复制标题
DOI：
10.1016/0021-9290(84)90009-5
复制
发表时间：
1984-01-01
影响因子：
2.4
通讯作者：
LUTTGES, MW
中科院分区：
文献类型：
--
作者：
BEEL, JA;GROSWALD, DE;LUTTGES, MW
对损伤神经的力学特性进行了研究。在单侧神经挤压后的特定时间，对小鼠坐骨神经进行机械测试。当神经节段被拉长至机械失效时，获得照片和纵向力测量值。比例极限的应力和应变以及表观弹性模量被用作强度、弹性和刚度的指标。损伤导致强度和刚度的时间依赖性增加，弹性降低。这些变化在受损和对侧未受损神经中明显。许多变化似乎与神经外膜有关。神经中的一些机械变化可能对神经和机械接口结构的完整性和功能产生重要影响。
Mechanical properties of injured nerves were studied. At specific times following unilateral nerve crush, sciatic nerves of mice were tested mechanically. Photographs and longitudinal force measurements were obtained as nerve segments were elongated to mechanical failure. Stress and strain at the proportional limit and apparent elastic modulus were used as indicators of strength, elasticity and stiffness. Injury led to time-dependent increases in strength and stiffness and decreases in elasticity. These changes were apparent in damaged and contralateral, undamaged nerves. Many of the changes appear to be related to the epineurium. Some mechanical changes in nerve could have important consequences for the integrity and function of nerves and mechanically interfaced structures.