MECHANICAL-BEHAVIOR OF DAMAGED TRABECULAR BONE
MECHANICAL-BEHAVIOR OF DAMAGED TRABECULAR BONE
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DOI：
10.1016/0021-9290(94)90040-x
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发表时间：
1994-11-01
影响因子：
2.4
通讯作者：
HAYES, WC
中科院分区：
文献类型：
--
作者：
KEAVENY, TM;WACHTEL, EF;HAYES, WC
受损的骨小梁的力学行为可能在老年性脊柱骨折的病因中起作用，因为受损的骨存在于并可能削弱老年椎体。为了描述受损小梁骨的一些特征，我们测量了当牛小梁骨被加载到超出其弹性范围的各种应变时，其模量和强度的变化。取自17个不同骨骼的23个缩小切片标本，加载0-X-0-9%菌株，其中X为1.0% （n = 7）、2.5% （n = 6）、4.0% （n = 5）和5.5% (n = 5) 4种菌株之一。我们发现，模量降低了所有施加的应变，而强度降低只有应变水平大于或等于2.5%；模量和强度的百分比变化与杨氏模量无关，但高度依赖于外加应变的大小；模量的降低总是大于强度的降低；简单的统计模型，只使用应用应变的知识，很好地预测了模量（r(2) = 0.97）和强度（r(2) = 0.74）的百分比降低。本文报道的模量降低与皮质骨在拉伸载荷下的模量降低在定性上一致，支持了低应变（小于或等于4.0%）下皮质骨和小梁骨的损伤行为相似的概念。此外，由于模量的减少总是大于强度的减少，受损的小梁骨可能在体内通过将应力重新分配给未受损的骨而受到应力保护。
The mechanical behavior of damaged trabecular bone may play a role in the etiology of age-related spine fractures since damaged bone exists in and may weaken the elderly vertebral body. To describe some characteristics of damaged trabecular bone, we measured the changes in modulus and strength that occur when bovine trabecular bone is loaded in compression to various strains beyond its elastic range. Twenty-three reduced-section specimens, taken from 17 different bones, were loaded from 0-X-0-9% strain, where X was one of four strains: 1.0% (n = 7), 2.5% (n = 6), 4.0% (n = 5), or 5.5% (n = 5). We found that modulus was reduced for all applied strains, whereas strength was reduced only for strain levels greater than or equal to 2.5%; the percentage changes in modulus and strength were independent of Young's modulus but were highly dependent on the magnitude of the applied strains; modulus was always reduced more than strength; and simple statistical models, using knowledge of only the applied strains, predicted well the percentage reductions in modulus (r(2) = 0.97) and strength (r(2) = 0.74). The modulus reductions reported here are in qualitative agreement with those for cortical bone in tensile loading, supporting the concept that the damage behaviors of cortical and trabecular bone are similar for low strains (less than or equal to 4.0%). In addition, because modulus was always reduced more than strength, damaged trabecular bone may be stress protected in vivo by redistribution of stresses to undamaged bone.