In vivo measurement of phosphorous markers of disease.
In vivo measurement of phosphorous markers of disease.
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DOI：
10.1155/2004/419095
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发表时间：
2003
期刊：
影响因子：
--
通讯作者：
Brown TR
中科院分区：
文献类型：
--
作者：
Arias-Mendoza F;Brown TR
磷磁共振波谱（31 P-MRS）已被用于研究能量，碳水化合物和磷脂代谢在体外和体内活组织中的非侵入性。尽管它缺乏灵敏度，但自从设计了适当的信号定位以来，它的应用已经扩展到原位人体组织和器官。在神经肌肉疾病和精神分裂症的磷酸肌酸的后续行动和后续的磷脂相关分子在肿瘤中的描述，以证明31 P-MRS作为一种成像技术，以确定在体内的疾病标记物的价值，并在诊断，预后和人类疾病的后续行动。
Phosphorus Magnetic Resonance Spectroscopy (31P-MRS) has been utilized to study energy, carbohydrate, and phospholipid metabolism in vitro and in vivo in live tissues non-invasively. Despite its lack of sensitivity, its application has extended to in situ human tissues and organs since proper signal localization was devised. Follow-up of phosphocreatine in neuromuscular diseases and schizophrenia and follow-up of phospholipid-related molecules in tumors are described here to demonstrate the value of 31P-MRS as an imaging technique to determine in vivo markers of disease and in the diagnosis, prognosis, and follow-up of human diseases.