Patient outcomes after hospitalisation with COVID-19 and implications for follow-up: results from a prospective UK cohort.
Patient outcomes after hospitalisation with COVID-19 and implications for follow-up: results from a prospective UK cohort.
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DOI：
10.1136/thoraxjnl-2020-216086
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发表时间：
2021-04
期刊：
影响因子：
10
通讯作者：
Barratt SL
中科院分区：
文献类型：
--
作者：
Arnold DT;Hamilton FW;Milne A;Morley AJ;Viner J;Attwood M;Noel A;Gunning S;Hatrick J;Hamilton S;Elvers KT;Hyams C;Bibby A;Moran E;Adamali HI;Dodd JW;Maskell NA;Barratt SL
SARS-CoV-2感染的长期后果尚不确定。这项观察性研究前瞻性招募了因COVID-19住院的连续性患者（n=163）。在入院后8-12周，邀请幸存者进行系统的临床随访。在131名参与者中，110人参加了后续诊所。大多数（74%）有持续的症状（特别是呼吸困难和过度疲劳）和身体能力的限制。然而，胸片、运动试验、血液检查和肺功能测定的临床显著异常不太常见（35%），尤其是在急性感染期间不需要补充氧气的患者（7%）。结果表明，注重康复和总体福祉的整体方法至关重要。
The longer-term consequences of SARS-CoV-2 infection are uncertain. Consecutive patients hospitalised with COVID-19 were prospectively recruited to this observational study (n=163). At 8–12 weeks postadmission, survivors were invited to a systematic clinical follow-up. Of 131 participants, 110 attended the follow-up clinic. Most (74%) had persistent symptoms (notably breathlessness and excessive fatigue) and limitations in reported physical ability. However, clinically significant abnormalities in chest radiograph, exercise tests, blood tests and spirometry were less frequent (35%), especially in patients not requiring supplementary oxygen during their acute infection (7%). Results suggest that a holistic approach focusing on rehabilitation and general well-being is paramount.