Ecological association between asbestos-related diseases and historical asbestos consumption: an international analysis
Ecological association between asbestos-related diseases and historical asbestos consumption: an international analysis
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DOI：
10.1016/s0140-6736(07)60412-7
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发表时间：
2007-03-10
期刊：
影响因子：
168.9
通讯作者：
Ohtaki, Megu
中科院分区：
文献类型：
--
作者：
Lin, Ro-Ting;Takahashi, Ken;Ohtaki, Megu
与石棉有关的疾病可能在全球流行，这一点日益受到关注。我们的目的是评估与石棉相关疾病的国家死亡率与石棉历史消费之间的生态关联。方法我们计算了所有有数据的国家按性别划分的年年龄调整死亡率（每年每百万人口死亡人数）（胸膜、腹膜和所有间皮瘤以及石棉沉着病）以及1960-69年的人均石棉消费量（每人每年千克）。我们对特定疾病的死亡率进行了回归分析，并根据性别特异性国家人口的规模进行加权。结果：历史石棉消费量是男女间皮瘤死亡的重要预测因素（调整后的R-2= 0. 74，p
Background The potential for a global epidemic of asbestos-related diseases is a growing concern. Our aim was to assess the ecological association between national death rates from diseases associated with asbestos and historical consumption of asbestos.Methods We calculated, for all countries with data, yearly age-adjusted mortality rates by sex (deaths per million population per year) for each disease associated with asbestos (pleural, peritoneal, and all mesothelioma, and asbestosis) in 2000-04 and mean per head asbestos consumption (kg per person per year) in 1960-69. We regressed death rates for the specified diseases against historical asbestos consumption, weighted by the size of sex-specific national populations.Findings Historical asbestos consumption was a significant predictor of death for all mesothelioma in both sexes (adjusted R-2=0.74, p