The influence of amino acids on the biomineralization of hydroxyapatite in gelatin
The influence of amino acids on the biomineralization of hydroxyapatite in gelatin
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DOI：
10.1016/s0162-0134(02)00481-6
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发表时间：
2002-08-30
影响因子：
3.9
通讯作者：
Felsche, J
中科院分区：
文献类型：
--
作者：
Eiden-Assmann, S;Viertelhaus, M;Felsche, J
pH值对磷酸钙相的影响。在双扩散实验中，研究了Tris和氨基酸如天冬氨酸、谷氨酸和丝氨酸对羟基磷灰石形成和形态的影响。在该系统中，羟基磷灰石仅在反应持续时间的pH值为7.4左右或更高时形成。pH值的降低导致羟基磷灰石转化为磷酸八钙。氨基酸和三羟甲基氨基甲烷或三羟甲基氨基甲烷的缓冲能力对合成羟基磷灰石的形态有影响。添加剂的存在导致取决于反应系统的由针、刀片或板组成的球体。(C)2002年爱思唯尔科技有限公司All rights reserved.
The effects of pH on the calcium phosphate phase. of Tris and of amino acids, such as aspartic acid, glutamic acid, and serine on hydroxyapatite formation and morphology, were studied in double diffusion experiments, In this system, hydroxyapatite was only formed when the pH was around 7.4 or higher for the duration of the reaction. A decrease in pH resulted in the transformation of hydroxyapatite to octacalcium phosphate. Amino acids and Tris or the buffering capacity of Tris have an effect on the morphology of the synthetic hydroxyapatite. The presence of the additive results in spheres consisting of needles, blades or plates depending on the reaction system. (C) 2002 Elsevier Science Inc. All rights reserved.