Review on nanoparticles and nanostructured materials: history, sources, toxicity and regulations.

Review on nanoparticles and nanostructured materials: history, sources, toxicity and regulations.
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DOI:
10.3762/bjnano.9.98
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发表时间:
2018
影响因子:
3.1
通讯作者:
Danquah MK
Danquah MK
中科院分区:
材料科学3区
文献类型:
--
作者:
Jeevanandam J;Barhoum A;Chan YS;Dufresne A;Danquah MK

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纳米材料(NM)由于其可调的物理,化学和生物学特性而在技术进步中获得了突出地位,并且其性能优于其大块对应物。NM根据其大小、组成、形状和来源进行分类。预测NM的独特性质的能力增加了每个分类的价值。由于NM的生产及其工业应用的增长,与毒性有关的问题是不可避免的。本综述的目的是比较合成(工程)和天然存在的纳米粒子(NP)和纳米结构材料(NSMs),以确定其纳米级特性,并定义与环境中的NP和NSMs风险评估相关的具体知识差距。该综述概述了纳米物质的历史和分类,并概述了纳米颗粒和非磁性物质的各种来源,从天然到合成,以及它们对哺乳动物细胞和组织的毒性作用。此外,还讨论了与NP和NSM相关的毒性反应类型以及不同国家为降低相关风险而实施的法规。
Nanomaterials (NMs) have gained prominence in technological advancements due to their tunable physical, chemical and biological properties with enhanced performance over their bulk counterparts. NMs are categorized depending on their size, composition, shape, and origin. The ability to predict the unique properties of NMs increases the value of each classification. Due to increased growth of production of NMs and their industrial applications, issues relating to toxicity are inevitable. The aim of this review is to compare synthetic (engineered) and naturally occurring nanoparticles (NPs) and nanostructured materials (NSMs) to identify their nanoscale properties and to define the specific knowledge gaps related to the risk assessment of NPs and NSMs in the environment. The review presents an overview of the history and classifications of NMs and gives an overview of the various sources of NPs and NSMs, from natural to synthetic, and their toxic effects towards mammalian cells and tissue. Additionally, the types of toxic reactions associated with NPs and NSMs and the regulations implemented by different countries to reduce the associated risks are also discussed.
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